MICHELE L. LEMONS
Assistant Professor of Biology (2007)
Department of Natural Sciences
B.S., The College of William and Mary, Biology major, Psychology minor, Education degree and certification, 1993
Ph.D., University of Florida, Neuroscience, 1999
Ph.D. dissertation title: “Inhibition of regeneration in the injured, adult spinal cord: potential role of chondroitin sulfate proteoglycans, specifically aggrecan.”
Sample of Courses Taught
Undergraduate: Human Biology in Health and Disease, General Physiology, Principles of Neuroscience, and Concepts in Biology
Sample of Publications
M.L. Lemons and M.L. Condic. (2007) Integrin signaling is integral to regeneration. Experimental Neurology, 209(2): 343-52.
M.L. Lemons and M.L. Condic. (2006) Combined integrin activation and intracellular cAMP cause Rho GTPase dependent growth cone collapse on laminin-1. Experimental Neurology, 202(2): 324-35.
M.L. Lemons, M.L Abanto, S. Barua, W. Halfter and M.L. Condic (2005). Adaptation of sensory neurons to hyalectin and decorin proteoglycans. Journal of Neuroscience 25 (20), 4964-73.
M.L. Lemons, J.D. Sandy, D.K. Anderson and D.R. Howland (2003). Intact aggrecan and chondroitin-sulfate depleted aggrecan inhibit axon growth in the adult rat spinal cord. Experimental Neurology 184(2):981-90.
M.L. Condic and M.L. Lemons (2002). Extracellular matrix in spinal cord regeneration: getting beyond attraction and inhibition. Review paper submitted per request, Neuroreport 13 (3), A37-48.
M.L. Lemons, J.D. Sandy, D.K. Anderson and D.R. Howland (2001). Intact Aggrecan and Fragments Generated by Both Aggrecanase and Metalloproteinase-Like Activities Are Present in the Developing and Adult Rat Spinal Cord and Their Relative Abundance is Altered by Injury. Journal of Neuroscience 21 (13), 4772-4781.
M.L. Lemons, D.R. Howland, D.K. Anderson. Chondroitin Sulfate Proteoglycan Immunoreactivity Increases Following Spinal Cord Injury and Transplantation (1999). Experimental Neurology 160, 51-65.
Sample of Presentations
2005 Neurons on the move: how growth cones find their way.
2005 Netrin-1 mediated growth cone collapse involves integrins and other netrin receptors. University of Utah.
2004 Rho GTPases, cAMP and integrins interact and influence growth cone motility. University of Utah.
2002 Cytoplasmic cAMP Levels Influence Embryonic Regeneration. Park City, Utah.
2001 Influence of Extrinsic and Intrinsic Factors on Regeneration. University of Utah.
2000 The Influence of Chondroitin Sulfate Proteoglycans, Specifically Aggrecan, upon Spinal Cord Regeneration. University of Utah.